PER2 Antikörper (AA 13-330)

Produktnummer ABIN3043602

Produktdetails anti-PER2 Antikörper

Target: PER2 (Period Circadian Protein 2 (PER2))

Bindungsspezifität: AA 13-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PER2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Period circadian protein homolog 2(PER2) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Period circadian protein homolog 2(PER2) detection. Tested with WB in Human.
Gene Name: period circadian clock 2
Protein Name: Period circadian protein homolog 2

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PER2 recombinant protein (Position: N13-K330). Human PER2 shares 84% and 83% amino acid (aa) sequence identity with mouse and rat PER2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PER2 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Andere Bezeichnung: PER2 (PER2 Produkte)

Synonyme: FASPS antikoerper, FASPS1 antikoerper, mKIAA0347 antikoerper, mPer2 antikoerper, rPER2 antikoerper, gPer2 antikoerper, fj43b09 antikoerper, wu:fj43b09 antikoerper, period circadian regulator 2 antikoerper, period circadian clock 2 antikoerper, PER2 antikoerper, Per2 antikoerper, per2 antikoerper

Hintergrund: The PER2 gene encodes the period circadian protein homolog 2 protein in humans. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. PER2 is mapped to 2q37.3. It has been showed that PER2 can positively stimulate activity of the Bmal1-Npas2 transcription complex and, in turn, Npas2 transcriptionally regulates delta-aminolevulinate synthase. PER2 is involved in a negative-feedback loop that attenuates estrogen stimulation and links the circadian cycle to estrogen receptor signaling. The rhythmic levels of PER2 are critical for circadian oscillations in cells and intact organisms. What's more, the PER2 gene also functions in tumor suppression by regulating DNA damage-responsive pathways.

Synonyms: Circadian clock protein PERIOD 2 antibody|FASPS antibody|FASPS1 antibody|hPER 2 antibody|hPER2 antibody|KIAA0347 antibody|OTTHUMP00000164476 antibody|PER 2 antibody|PER2 antibody|PER2_HUMAN antibody|Period 2 antibody|Period 2 isoform 1 antibody|Period circadian clock 2 antibody|Period circadian protein 2 antibody|Period circadian protein homolog 2 antibody|Period homolog 2 (Drosophila) antibody|Period homolog 2 antibody|Period2 antibody

Gen-ID: 8864

UniProt: O15055