SSTR2 Antikörper (Middle Region)
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- Target Alle SSTR2 Antikörper anzeigen
- SSTR2 (Somatostatin Receptor 2 (SSTR2))
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Bindungsspezifität
- AA 184-198, Middle Region
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SSTR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Somatostatin receptor type 2(SSTR2) detection. Tested with WB in Human,Mouse,Rat.
- Sequenz
- RSNQWGRSSC TINWP
- Kreuzreaktivität (Details)
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Predicted Cross Reactivity: human, mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Produktmerkmale
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Rabbit IgG polyclonal antibody for Somatostatin receptor type 2(SSTR2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: somatostatin receptor 2
Protein Name: Somatostatin receptor type 2(SS-2-R/SS2-R/SS2R) - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human Somatostatin Receptor 2(184-198aa RSNQWGRSSCTINWP), identical to the related rat and mouse sequences.
- Isotyp
- IgG
- Top Product
- Discover our top product SSTR2 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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Occludin downregulation in high glucose is regulated by SSTR2 via the VEGF/NRP1/Akt signaling pathway in RF/6A cells." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 1732-1738, (2017) (PubMed).
: "Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 7, pp. 4071-5, (2013) (PubMed).
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Occludin downregulation in high glucose is regulated by SSTR2 via the VEGF/NRP1/Akt signaling pathway in RF/6A cells." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 1732-1738, (2017) (PubMed).
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- Target
- SSTR2 (Somatostatin Receptor 2 (SSTR2))
- Andere Bezeichnung
- SSTR2 (SSTR2 Produkte)
- Synonyme
- Smstr2 antikoerper, SSTR-2 antikoerper, Smstr-2 antikoerper, sst2 antikoerper, SS2R antikoerper, SSTR2 antikoerper, MGC80373 antikoerper, somatostatin receptor 2 antikoerper, somatostatin receptor 2 L homeolog antikoerper, SSTR2 antikoerper, Sstr2 antikoerper, sstr2.L antikoerper
- Hintergrund
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SSTR2(Somatostatin receptor type 2) is a protein that in humans is encoded by the SSTR2 gene. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. Stable SSTR2 transfection of human pancreatic cells, which do not endogenously express SSTR2, inhibits cell proliferation, tumorigenicity, and metastasis. These effects occur as a consequence of an autocrine SSTR2-dependent loop, whereby SSTR2 induces expression of its own ligand, somatostatin.SSTR2 mRNA was variably expressed in all neuroblastoma tumors with a relevant reduction in the more advanced stage.
Synonyms: Somatostatin receptor type 2 antibody|SRIF-1 antibody|SRIF1 antibody|SS-2-R antibody|SS2-R antibody|SS2R antibody|SSR2_HUMAN antibody|SST2 antibody|SSTR2 antibody - UniProt
- P30874
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