Chemokine (C-C Motif) Ligand 8 (CCL8) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2792194, Anbieter: Anmelden zum Anzeigen
Antigen
  • HC14
  • MCP-2
  • MCP2
  • SCYA10
  • SCYA8
  • 1810063B20Rik
  • AB023418
  • Mcp2
  • Scya8
  • chemokine (C-C motif) ligand 8
  • monocyte chemoattractant protein-2 precursor
  • CCL8
  • Ccl8
  • MCP-2
Epitop
Middle Region
15
6
6
5
2
1
1
1
1
Reaktivität
Human
92
51
3
2
1
Wirt
Kaninchen
73
39
15
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
15
7
6
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
102
58
15
14
8
7
4
4
4
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CCL8
Sequenz SYTRITNIQC PKEAVIFKTK RGKEVCADPK ERWVRDSMKH LDQIFQNLKP
Homologie Human: 100%
Produktmerkmale This is a rabbit polyclonal antibody against CCL8. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung CCL8 (CCL8 Antibody Abstract)
Hintergrund CCL8 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC14, MCP-2, MCP2, SCYA10, SCYA8
Protein Interaction Partner: ACKR2, ACKR4, CCR5, CCR3, CCR2, CCR1, MMP3, VCAN, ACKR1,
Protein Size: 99
Molekulargewicht 9 kDa
Gen-ID 6355
NCBI Accession NM_005623, NP_005614
UniProt P80075
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 99 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (Middle Region) antibody (ABIN2792194) anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (Middle Region) antibody
Allgemeine Veröffentlichungen Hori, Naishiro, Sohma, Suzuki, Hatakeyama, Yamamoto, Sonoda, Mizue, Imai, Tsutsumi, Kokai: "CCL8 is a potential molecular candidate for the diagnosis of graft-versus-host disease." in: Blood, Vol. 111, Issue 8, pp. 4403-12, 2008 (PubMed).

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