MDS1 and EVI1 Complex Locus (MECOM) (N-Term) Antikörper

Details zu Produkt Nr. ABIN2787657, Anbieter: Anmelden zum Anzeigen
Antigen
  • evi1
  • im:7140716
  • prdm3
  • EVI1
  • AML1-EVI-1
  • MDS1
  • MDS1-EVI1
  • PRDM3
  • D630039M04Rik
  • Evi-1
  • Evi1
  • Jbo
  • Mds
  • Mds1
  • Mds1-Evi1
  • Prdm3
  • Znfpr1b1
  • AML1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • MDS1 and EVI1 complex locus
  • runt-related transcription factor 1
  • mecom
  • MECOM
  • LOC100343228
  • Mecom
  • RUNX1
Epitop
N-Term
28
17
17
15
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
105
33
8
3
3
2
2
1
1
1
Wirt
Kaninchen
71
31
15
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
6
6
6
6
6
Applikation
Western Blotting (WB)
104
65
11
6
3
2
1
1
1
1
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human EVI1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN976488.
Sequenz VKGLSSTEQT NKSQSPLMTH PQILPATQDI LKALSKHPSV GDNKPVELQP
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against EVI1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung EVI1 (MECOM Antibody Abstract)
Hintergrund EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
Alias Symbols: AML1-EVI-1, EVI-1, MDS1-EVI1, MGC163392, PRDM3, EVI1, MDS1
Protein Interaction Partner: PRMT1, PIAS4, SUMO1, SOX2, ELAVL1, SIRT1, KAT2B, SMAD4, SMAD3, SMAD2, SMAD1, EHMT2, SUV39H1, MECOM, HDAC1, HDAC4, CTBP2, CTBP1, CREBBP, MBD3,
Protein Size: 1051
Molekulargewicht 118 kDa
Gen-ID 2122
NCBI Accession NM_005241, NP_005232
UniProt Q03112
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1051 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (N-Term) Antikörper (ABIN2787657) WB Suggested Anti-EVI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Allgemeine Veröffentlichungen Sato, Goyama, Nitta, Takeshita, Yoshimi, Nakagawa, Kawazu, Ichikawa, Kurokawa: "Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling." in: Cancer science, Vol. 99, Issue 7, pp. 1407-13, 2008 (PubMed).