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CBX2 Antikörper (Middle Region)

CBX2 Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787656
  • Target Alle CBX2 Antikörper anzeigen
    CBX2 (Chromobox Homolog 2 (CBX2))
    Bindungsspezifität
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 59
    • 22
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Rind (Kuh), Pferd, Schwein
    Wirt
    • 53
    • 5
    • 1
    Kaninchen
    Klonalität
    • 51
    • 7
    • 1
    Polyklonal
    Konjugat
    • 27
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CBX2 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 38
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    SDSDPDSASP PSTGQNPSVS VQTSQDWKPT RSLIEHVFVT DVTANLITVT
    Homologie
    Cow: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CBX2. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CBX2
    Top Product
    Discover our top product CBX2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 532 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CBX2 (Chromobox Homolog 2 (CBX2))
    Andere Bezeichnung
    CBX2 (CBX2 Produkte)
    Synonyme
    cbx2 antikoerper, M33 antikoerper, pc1 antikoerper, wu:fd20e09 antikoerper, zgc:103563 antikoerper, MOD2 antikoerper, pc antikoerper, CDCA6 antikoerper, SRXY5 antikoerper, cdca6 antikoerper, m33 antikoerper, chromobox 2 antikoerper, chromobox homolog 2 (Drosophila Pc class) antikoerper, chromobox 2 L homeolog antikoerper, cbx2 antikoerper, CBX2 antikoerper, Cbx2 antikoerper, cbx2.L antikoerper
    Hintergrund
    CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
    Alias Symbols: CDCA6, M33, MGC10561, SRXY5
    Protein Interaction Partner: KRTAP10-3, KRTAP10-1, KRTAP10-9, KRTAP10-7, RBMY1F, DHX57, KRTAP2-4, RBMY1A1, RNF2, BMI1, MDFI, SOX2, GTF2I, PHC2, CSNK2B, CSNK2A2, CSNK2A1, CENPE, PARP1, CCDC158, DIS3L2, HIST4H4, CBX2, PARP12, RNF213, ZKSCAN7, DCAF6, KDM3A, MYCBP2, ANKRD26, PSME3, TRANK
    Protein Size: 532
    Molekulargewicht
    56 kDa
    Gen-ID
    84733
    NCBI Accession
    NM_005189, NP_005180
    UniProt
    Q14781
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