MED14 Antikörper (Mediator Complex Subunit 14) (Middle Region)

Details for Product anti-MED14 Antibody No. ABIN2787568, Anbieter: Anmelden zum Anzeigen
Antigen
  • CG12031
  • Dmel\\CG12031
  • Med14
  • Trap170
  • dTRAP170
  • p160
  • EXLM1
  • crsp150
  • crsp2
  • trap170
  • wu:fd21c05
  • wu:fk28h11
  • CRSP2
  • NV18605
  • CRSP150
  • CSRP
  • CXorf4
  • DRIP150
  • RGR1
  • TRAP170
  • 9930001L01Rik
  • AU041628
  • Crsp2
  • ENSMUSG00000073278
  • Gm641
  • ORF1
  • RGD1560170
  • Mediator complex subunit 14
  • mediator complex subunit 14
  • mediator of RNA polymerase II transcription subunit 14
  • transcriptional regulation
  • MED14
  • med14
  • LOC100113592
  • Med14
  • RGR1
Epitop
Middle Region
15
10
10
4
2
2
1
1
1
1
Reaktivität
Human, Maus, Kaninchen
34
27
4
1
1
1
1
1
Wirt
Kaninchen
38
6
Klonalität
Polyklonal
Konjugat
Dieser MED14 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
30
23
9
8
2
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MED14
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN979938.
Sequenz AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE
Homologie Human: 100%, Mouse: 79%, Rabbit: 86%
Produktmerkmale This is a rabbit polyclonal antibody against MED14. It was validated on Western Blot.
Reinigung Affinity Purified
Andere Bezeichnung MED14 (MED14 Antibody Abstract)
Hintergrund The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Alias Symbols: CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, MGC104513, RGR1, TRAP170
Protein Interaction Partner: UBC, HECW2, CDK8, CDK19, MED12, ESR1, MED19, MED26, PPARG, FBXW7, EPAS1, MED11, MED8, MED29, MED18, MED4, PPP6R1, MED16, MED13, MED24, MED27, MED17, MED21, MED1, CTDP1, SREBF1, DCTN1, ACTN2, ACTN1, MED10, UACA, NECAB2, MED25, MED15, CRSP5, MED7, MED23, VD
Protein Size: 1454
Molekulargewicht 160 kDa
Gen-ID 9282
NCBI Accession NM_004229, NP_004220
UniProt O60244
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1454 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Mediator Complex Subunit 14 (MED14) (Middle Region) antibody (ABIN2787568) WB Suggested Anti-MED14 Antibody Titration: 0.2-1 ug/ml
Positive Control...
Western Blotting (WB) image for anti-Mediator Complex Subunit 14 (MED14) (Middle Region) antibody (ABIN2787568) WB Suggested Anti-MED14
Antibody Titration: 0.2-1 µg/mL
Positive Contro...
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