TRIB3 Antikörper (N-Term)

Produktnummer ABIN2787259

Produktdetails anti-TRIB3 Antikörper

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Schaf, Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Rabbit: 86%, Rat: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIB3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 358 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIB3

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Andere Bezeichnung: TRIB3 (TRIB3 Produkte)

Synonyme: zgc:76966 antikoerper, TRIB3 antikoerper, C20orf97 antikoerper, NIPK antikoerper, SINK antikoerper, SKIP3 antikoerper, TRB3 antikoerper, Ifld2 antikoerper, Nipk antikoerper, TRB-3 antikoerper, Trb3 antikoerper, tribbles pseudokinase 3 antikoerper, trib3 antikoerper, TRIB3 antikoerper, Trib3 antikoerper

Hintergrund: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
Alias Symbols: C20orf97, NIPK, SINK, SKIP3, TRB3
Protein Interaction Partner: RPGRIP1, UBC, DDIT3, ATF4, RFWD2, PRMT5, AKT1, APP, SMURF1, CDC25A, BMPR2, SMAD3, BCL6, COPS6, RBM48, EEF1G, SETDB1, GIT1, GDF9, KAT5, AKT2, RELA, ATF5, HRSP12, TIAF1, MCM3AP, LTBP4, SIAH1, RBM4, PSMA3, RPSA, HLA-B, GRN, FN1, CSNK2B,
Protein Size: 358

Molekulargewicht: 39 kDa

Gen-ID: 57761

NCBI Accession: NM_021158, NP_066981

UniProt: Q96RU7

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha