SULT1E1 Antikörper (Middle Region)

Produktnummer ABIN2783458

Produktdetails anti-SULT1E1 Antikörper

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SULT1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LMVAGHPNPG SFPEFVEKFM QGQVPYGSWY KHVKSWWEKG KSPRVLFLFY

Homologie: Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against SULT1E1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SULT1E1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 294 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SULT1E1 Antikörper (ABIN2783458)

Yalcin, Kulkarni, Slitt, King: "Bisphenol A sulfonation is impaired in metabolic and liver disease." in: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, (2016) (PubMed).

Yalcin, More, Neira, Lu, Cherrington, Slitt, King: "Downregulation of sulfotransferase expression and activity in diseased human livers." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 9, pp. 1642-50, (2013) (PubMed).

Details zu SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Andere Bezeichnung: SULT1E1 (SULT1E1 Produkte)

Synonyme: STE antikoerper, St1 antikoerper, EST antikoerper, ST1E1 antikoerper, Ste antikoerper, EST-1 antikoerper, est-1 antikoerper, ste antikoerper, sult1e1 antikoerper, sult1e1.S antikoerper, sulfotransferase family 1E member 1 antikoerper, sulfotransferase family 1E, estrogen-preferring, member 1 antikoerper, estrogen sulfotransferase antikoerper, sulfotransferase family 1E, member 1 antikoerper, sulfotransferase family 1E member 1 L homeolog antikoerper, Sult1e1 antikoerper, SULT1E1 antikoerper, St1 antikoerper, CpipJ_CPIJ012993 antikoerper, CpipJ_CPIJ014515 antikoerper, LOC482182 antikoerper, sult1e1.L antikoerper

Hintergrund: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
Alias Symbols: EST, EST-1, MGC34459, STE, ST1E1
Protein Interaction Partner: PDE9A, LRIF1, COPS6, RBM48, IGSF21, ENOX1, SETDB1, C14orf1, SULT2B1, UNC119, BMPR2, TP53, EEF1A1,
Protein Size: 294

Molekulargewicht: 35 kDa

Gen-ID: 6783

NCBI Accession: NM_005420, NP_005411

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis