TPI1 Antikörper (N-Term)

Produktnummer ABIN2783242

Produktdetails anti-TPI1 Antikörper

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Bindungsspezifität: N-Term

Reaktivität: Human, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TPI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 249 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TPI1 Antikörper (ABIN2783242)

Ralser, Nebel, Kleindorp, Krobitsch, Lehrach, Schreiber, Reinhardt, Timmermann: "Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans." in: BMC genetics, Vol. 9, pp. 38, (2008) (PubMed).

Details zu TPI1

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Andere Bezeichnung: TPI1 (TPI1 Produkte)

Synonyme: TIM antikoerper, TPI antikoerper, TIM1 antikoerper, hTIM antikoerper, tpi antikoerper, tpi1 antikoerper, TPI1 antikoerper, AI255506 antikoerper, Tpi antikoerper, Tpi-1 antikoerper, GB17473 antikoerper, Tim antikoerper, CG2171 antikoerper, Dmel\\CG2171 antikoerper, ND14 antikoerper, TPIS antikoerper, sgk antikoerper, wstd antikoerper, DrTPI-A antikoerper, DrTPI-B antikoerper, TIM-B antikoerper, cb179 antikoerper, wu:fb51c02 antikoerper, triosephosphate isomerase 1 antikoerper, timeless circadian regulator antikoerper, triosephosphate isomerase 1 S homeolog antikoerper, triosephosphate isomerase antikoerper, triose-phosphate isomerase antikoerper, Triose-phosphate isomerase antikoerper, triose-phosphate isomerase, putative antikoerper, timeless circadian clock antikoerper, Triose phosphate isomerase antikoerper, Triosephosphate isomerase antikoerper, triosephosphate isomerase 1a antikoerper, triosephosphate isomerase 1b antikoerper, TPI1 antikoerper, TIMELESS antikoerper, tpi1 antikoerper, Tpi1 antikoerper, tpi1.S antikoerper, Tpi antikoerper, tpiA antikoerper, CNE05000 antikoerper, Fnod_0738 antikoerper, Tlet_0996 antikoerper, SARE_RS16215 antikoerper, PKH_126640 antikoerper, Timeless antikoerper, tpi-1 antikoerper, tpi1a antikoerper, tpi1b antikoerper

Hintergrund: TPI1 belongs to the triosephosphate isomerase family. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
Alias Symbols: MGC88108, TPI, TIM
Protein Interaction Partner: MDM2, UBC, RNF2, EZH2, SUZ12, TARDBP, YWHAQ, SP1, UBD, HCVgp1, IQCB1, ATF2, LIG4, SSU72, SEC23IP, PDIA6, PRDX6, VCL, UBA52, TKT, PGK1, MPST, GPI, GAPDH, ENO1, APP, CUL1, CDK2, TERF1, POT1, PSMA3, MAPK6, PCNA, HDAC5, UCHL5, EGFR, LIPT1, SETDB1, DDX24, CFL1
Protein Size: 249

Molekulargewicht: 27 kDa

Gen-ID: 7167

NCBI Accession: NM_000365, NP_000356

UniProt: P60174

Pathways: Cell RedoxHomeostasis