AGPAT2 Antikörper (C-Term)

Produktnummer ABIN2781951

Produktdetails anti-AGPAT2 Antikörper

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Bindungsspezifität: C-Term

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGPAT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LEAIPTSGLT AADVPALVDT CHRAMRTTFL HISKTPQENG ATAGSGVQPA

Homologie: Human: 100%, Pig: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against AGPAT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AGPAT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 246 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AGPAT2

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Andere Bezeichnung: AGPAT2 (AGPAT2 Produkte)

Synonyme: AGPAT2 antikoerper, zgc:153984 antikoerper, 1-agpat2 antikoerper, bscl antikoerper, bscl1 antikoerper, lpaab antikoerper, lpaat-beta antikoerper, 1-AGPAT2 antikoerper, BSCL antikoerper, BSCL1 antikoerper, LPAAB antikoerper, LPAAT-beta antikoerper, 2510002J07Rik antikoerper, AV000834 antikoerper, 1-acylglycerol-3-phosphate O-acyltransferase 2 antikoerper, 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) antikoerper, AGPAT2 antikoerper, agpat2 antikoerper, Agpat2 antikoerper

Hintergrund: AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
Protein Interaction Partner: ABCG8, PHRF1, PHF11, ANKRD28, SLC23A2, GMPS, UBC,
Protein Size: 246

Molekulargewicht: 27 kDa

Gen-ID: 10555

NCBI Accession: NM_001012727, NP_001012745

UniProt: Q5VUD3