CCL17 Antikörper (N-Term)

Produktnummer ABIN2781510

Produktdetails anti-CCL17 Antikörper

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FIIKLIKWLM IAIPATFVNS AIRYLECKLA LAFRTRLVDH AYETYFTNQT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ABCD2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ABCD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 740 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Andere Bezeichnung: ABCD2 (CCL17 Produkte)

Synonyme: A-152E5.3 antikoerper, ABCD-2 antikoerper, SCYA17 antikoerper, TARC antikoerper, CCL17 antikoerper, Abcd-2 antikoerper, Scya17 antikoerper, Scya17l antikoerper, Tarc antikoerper, abcd2 antikoerper, C-C motif chemokine ligand 17 antikoerper, chemokine (C-C motif) ligand 17 antikoerper, ATP-binding cassette sub-family D member 2 antikoerper, CCL17 antikoerper, Ccl17 antikoerper, LOC100537809 antikoerper

Hintergrund: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
Alias Symbols: ABC39, ALDL1, ALDR, ALDRP, hALDR
Protein Interaction Partner: UBC, PXA1, PXA2, ABCD2, PEX19, ABCD1, ABCD3,
Protein Size: 740

Molekulargewicht: 83 kDa

Gen-ID: 225

NCBI Accession: NM_005164, NP_005155

UniProt: Q9UBJ2