MECOM Antikörper (N-Term)
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- Target Alle MECOM Antikörper anzeigen
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MECOM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA
- Homologie
- Human: 100%, Mouse: 93%, Zebrafish: 77%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MDS1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MDS1
- Top Product
- Discover our top product MECOM Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 169 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- Andere Bezeichnung
- MDS1 (MECOM Produkte)
- Synonyme
- AML1-EVI-1 antikoerper, EVI1 antikoerper, MDS1 antikoerper, MDS1-EVI1 antikoerper, PRDM3 antikoerper, D630039M04Rik antikoerper, Evi-1 antikoerper, Evi1 antikoerper, Jbo antikoerper, Mds antikoerper, Mds1 antikoerper, Mds1-Evi1 antikoerper, Prdm3 antikoerper, Znfpr1b1 antikoerper, evi1 antikoerper, im:7140716 antikoerper, prdm3 antikoerper, evi-1 antikoerper, mecom antikoerper, mecom-a antikoerper, mecom-b antikoerper, xEvi-1 antikoerper, evi1-B antikoerper, MDS1 and EVI1 complex locus antikoerper, MDS1 and EVI1 complex locus L homeolog antikoerper, MDS1 and EVI1 complex locus S homeolog antikoerper, MECOM antikoerper, Mecom antikoerper, mecom antikoerper, mecom.L antikoerper, mecom.S antikoerper
- Hintergrund
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MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
Alias Symbols: PRDM3, MDS1-EVI1
Protein Size: 169 - Molekulargewicht
- 19 kDa
- Gen-ID
- 4197
- NCBI Accession
- NM_004991, NP_004982
- UniProt
- Q13465
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