FOXA3 Antikörper (C-Term)

Produktnummer ABIN2779850

Produktdetails anti-FOXA3 Antikörper

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Bindungsspezifität: C-Term

Reaktivität: Human, Hund, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YNFNHPFSIN NLMSEQTSTP SKLDVGFGGY GAESGEPGVY YQSLYSRSLL

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Foxa3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Foxa3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FOXA3

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Andere Bezeichnung: Foxa3 (FOXA3 Produkte)

Synonyme: FOXA3 antikoerper, Zffkh1 antikoerper, fa11c04 antikoerper, fkd2 antikoerper, forkhead-2 antikoerper, wu:fa11c04 antikoerper, wu:fc37a08 antikoerper, zf-FKH1 antikoerper, FKHH3 antikoerper, HNF3G antikoerper, TCF3G antikoerper, HNF3-G antikoerper, Hnf-3g antikoerper, Hnf3g antikoerper, Tcf-3g antikoerper, Tcf3g antikoerper, forkhead box A3 antikoerper, FOXA3 antikoerper, foxa3 antikoerper, Foxa3 antikoerper

Hintergrund: Foxa3 is a transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Foxa3 is originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Foxa3 interacts with the cis-acting regulatory regions of these genes.Foxa3 is involved in glucose homeostasis, activates GLUT2 transcription and regulation of neuronal-specific transcription. Foxa3 is also involved in regulation of spermatogenesis, required for the maintenance of the testicular germ cell population and male fertility.
Alias Symbols: Hnf-3g, Hnf3g, Tcf-3g, Tcf3g
Protein Size: 353

Molekulargewicht: 37 kDa

Gen-ID: 15377

NCBI Accession: NM_008260, NP_032286

UniProt: P35584

Pathways: Carbohydrate Homeostasis