PAX4 Antikörper (Middle Region)

Produktnummer ABIN2779444

Produktdetails anti-PAX4 Antikörper

Target: PAX4 (Paired Box 4 (PAX4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RTIFSPSQAE ALEKEFQRGQ YPDSVARGKL ATATSLPEDT VRVWFSNRRA

Spezifität: 100 % homologous to all 3 isoforms (38, 30, 37 kDa).

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 343 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PAX4 Antikörper (ABIN2779444)

Zhang, Smyrk, Oliveira, Lohse, Zhang, Johnson, Lloyd: "KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers." in: The American journal of surgical pathology, Vol. 33, Issue 10, pp. 1562-9, (2010) (PubMed).

Details zu PAX4

Target: PAX4 (Paired Box 4 (PAX4))

Andere Bezeichnung: PAX4 (PAX4 Produkte)

Synonyme: KPD antikoerper, MODY9 antikoerper, Pax-4 antikoerper, PAX4 antikoerper, paired box 4 antikoerper, PAX4 antikoerper, Pax4 antikoerper

Hintergrund: PAX4 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing .- cells.
Alias Symbols: KPD, MGC129960, MODY9
Protein Interaction Partner: GMCL1,
Protein Size: 343

Molekulargewicht: 37 kDa

Gen-ID: 5078

NCBI Accession: NM_006193, NP_006184

UniProt: O43316