PSMA6 Antikörper (N-Term)

Produktnummer ABIN2778812

Produktdetails anti-PSMA6 Antikörper

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EYAFKAINQG GLTSVAVRGK DCAVIVTQKK VPDKLLDSST VTHLFKITEN

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMA6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMA6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 246 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Andere Bezeichnung: PSMA6 (PSMA6 Produkte)

Synonyme: IOTA antikoerper, PROS27 antikoerper, p27K antikoerper, psma6 antikoerper, psma6b antikoerper, zgc:91778 antikoerper, proteasome subunit alpha 6 antikoerper, proteasome (prosome, macropain) subunit, alpha type 6 antikoerper, proteasome subunit alpha 6a antikoerper, proteasome subunit alpha 6 L homeolog antikoerper, proteasome subunit alpha 6, like antikoerper, PSMA6 antikoerper, Psma6 antikoerper, psma6a antikoerper, psma6.L antikoerper, psma6l antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
Protein Interaction Partner: UBC, RNF170, LIMD2, C19orf57, TRIM39, ZBTB44, CADM1, HUWE1, PSMA3, RTP5, KRTAP4-2, AURKA, PSMD14, MDM2, PSMA5, PSMG3, PSMG2, PSMG1, RNF2, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA4, PSMA1, HNRNPA2B1, PYCRL, RPP38, RPP30, CAST, PS
Protein Size: 246

Molekulargewicht: 27 kDa

Gen-ID: 5687

NCBI Accession: NM_002791, NP_002782

UniProt: P60900

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA