ASH2L Antikörper (Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila)) (N-Term)

Details for Product anti-ASH2L Antibody No. ABIN2778326, Anbieter: Anmelden zum Anzeigen
Antigen
  • ASH2L
  • ash2-like
  • ASH2
  • ASH2L1
  • ASH2L2
  • Bre2
  • fb34c06
  • fe38b04
  • fi20h02
  • wu:fb34c06
  • wu:fe38b04
  • wu:fi20h02
  • zgc:171444
  • ash2 (absent, small, or homeotic)-like
  • ash2-like protein
  • hypothetical protein
  • ash2-like
  • ash2 (absent, small, or homeotic)-like (Drosophila)
  • ASH2L
  • ash2-like
  • ASH2-like
  • LOC100194676
  • LOC100338600
  • LOC100344501
  • LOC100348920
  • ash2l
  • Ash2l
Epitop
N-Term
22
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Ratte (Rattus)
86
50
30
14
12
11
7
4
3
2
2
2
2
1
1
1
Wirt
Kaninchen
76
11
2
Klonalität
Polyklonal
Konjugat
Dieser ASH2L Antikörper ist unkonjugiert
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
77
41
26
23
15
12
8
5
5
3
2
2
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ASH2L
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN973510.
Sequenz EPSSGEAEGG EANLVDVSGG LETESSNGKD TLEGAGDTSE VMDTQAGSVD
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against ASH2L. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung ASH2L (ASH2L Antibody Abstract)
Hintergrund ASH2L plays a role in hematopoiesis and is associated with some special kinds of leukemia. The amount of ASH2L transcripts is extremely high in fetal liver, testis, and leukemia cell lines with erythroid and megakaryocytic potential.
Alias Symbols: ASH2, ASH2L1, ASH2L2, Bre2
Protein Interaction Partner: CXXC1, DPY30, SETD1A, RBBP5, PPARG, KMT2A, KMT2D, UBC, SENP3, KDM6A, PPP1CC, SMAD9, KDM6B, WWP1, BRCA1, BARD1, WDR5, MEN1, USF1, KMT2C, HCFC2, SETD1B, KDM4B, KMT2B, HCFC1, ESR1, CDC73, HIST3H3, PYGO2, WDR82, PSMC5, PRMT1, E2F4, E2F1, PAGR1, NCOA6, PAXIP1,
Protein Size: 628
Molekulargewicht 69 kDa
Gen-ID 9070
NCBI Accession NM_004674, NP_004665
UniProt Q9UBL3
Forschungsgebiet Chromatin and Nuclear Signaling, Transcription Factors
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 628 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (N-Term) antibody (ABIN2778326) WB Suggested Anti-ASH2L Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Allgemeine Veröffentlichungen Yokoyama, Wang, Wysocka, Sanyal, Aufiero, Kitabayashi, Herr, Cleary: "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression." in: Molecular and cellular biology, Vol. 24, Issue 13, pp. 5639-49, 2004 (PubMed).

Haben Sie etwas anderes gesucht?