SMPD1 Antikörper (Middle Region)

Produktnummer ABIN2776371

Produktdetails anti-SMPD1 Antikörper

Target: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Kaninchen, Hund, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: INSTDPAGQL QWLVGELQAA EDRGDKVHII GHIPPGHCLK SWSWNYYRIV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 86%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SMPD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMPD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 631 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMPD1

Target: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Andere Bezeichnung: SMPD1 (SMPD1 Produkte)

Synonyme: ASM antikoerper, ASMASE antikoerper, NPD antikoerper, A-SMase antikoerper, Zn-SMase antikoerper, aSMase antikoerper, SMPD1 antikoerper, sphingomyelin phosphodiesterase 1 antikoerper, sphingomyelin phosphodiesterase 1, acid lysosomal antikoerper, sphingomyelin phosphodiesterase antikoerper, SMPD1 antikoerper, Smpd1 antikoerper, LOC5578088 antikoerper

Hintergrund: SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB).
Alias Symbols: ASM, NPD, ASMASE
Protein Interaction Partner: ELAVL1, DUSP23, NR1H2, ANXA7, ANXA4, NGFRAP1, ASAH1,
Protein Size: 631

Molekulargewicht: 65 kDa

Gen-ID: 6609

NCBI Accession: NM_000543, NP_000534

UniProt: P17405