RAG1 Antikörper (C-Term)
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- Target Alle RAG1 Antikörper anzeigen
- RAG1 (Recombination Activating Gene 1 (RAG1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Maus, Ratte, Schwein, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
- Homologie
- Horse: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Rag1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product RAG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1040 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RAG1 (Recombination Activating Gene 1 (RAG1))
- Andere Bezeichnung
- Rag1 (RAG1 Produkte)
- Synonyme
- RAG-1 antikoerper, rag1 antikoerper, RNF74 antikoerper, Rag-1 antikoerper, rag-1 antikoerper, rag1a antikoerper, recombination activating 1 antikoerper, recombination activating gene 1 antikoerper, recombination activating gene 1 S homeolog antikoerper, Rag1 antikoerper, RAG1 antikoerper, rag1 antikoerper, rag1.S antikoerper
- Hintergrund
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As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
Alias Symbols: Rag-1
Protein Interaction Partner: Gmeb1, Sf3a2, Kpna2, Rag1, UBE2C, UBE2H, UBE2E1, UBE2D2, UBE2D1, UBC, CDC34, Trav6-3, Rel, Nfkb1, Rela,
Protein Size: 1040 - Molekulargewicht
- 119 kDa
- Gen-ID
- 19373
- NCBI Accession
- NM_009019, NP_033045
- UniProt
- P15919
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