Tricellulin Antikörper (MARVELD2) (Middle Region)

Details for Product anti-MARVELD2 Antibody No. ABIN2775617, Anbieter: Anmelden zum Anzeigen
Antigen
  • Mrvldc2
  • BC003296
  • MARVD2
  • Tric
  • Trica
  • Tricb
  • Tricc
  • DFNB49
  • MRVLDC2
  • MARVEL domain containing 2
  • MARVEL (membrane-associating) domain containing 2
  • Marveld2
  • MARVELD2
Epitop
Middle Region
7
4
2
2
2
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
30
9
8
3
2
2
2
1
1
Wirt
Kaninchen
30
Klonalität
Polyklonal
Konjugat
Dieser Tricellulin Antikörper ist unkonjugiert
1
1
1
1
1
1
Applikation
Western Blotting (WB)
26
11
10
6
4
3
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MARVELD2
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN979833.
Sequenz PKTPFVLVVA GLAWITTIII LVLGMSMYYR TILLDSNWWP LTEFGINVAL
Homologie Cow: 100%, Dog: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
Produktmerkmale This is a rabbit polyclonal antibody against MARVELD2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung MARVELD2 (MARVELD2 Antibody Abstract)
Hintergrund Tight junctions (TJ) prevent leakage of solutes through the paracellular pathway of epithelial cells. MARVELD2, or tricellulin (TRIC), is an integral membrane protein concentrated at the vertically oriented TJ strands of tricellular contacts (Ikenouchi et
Alias Symbols: DFNB49, FLJ30532, MARVD2, MRVLDC2, Tric
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 457
Molekulargewicht 52 kDa
Gen-ID 153562
NCBI Accession NM_144724, NP_653325
UniProt C9J8H4
Forschungsgebiet Signaling
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 457 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Tricellulin (MARVELD2) (Middle Region) antibody (ABIN2775617) WB Suggested Anti-MARVELD2 Antibody Titration: 0.2-1 ug/ml
Positive Cont...
Allgemeine Veröffentlichungen Chishti, Bhatti, Tamim, Lee, McDonald, Leal, Ahmad: "Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families." in: Journal of human genetics, Vol. 53, Issue 2, pp. 101-5, 2008 (PubMed).

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