Hydroxyacid Oxidase 2 (HAO2) (N-Term) Antikörper

Details zu Produkt Nr. ABIN2773784, Anbieter: Anmelden zum Anzeigen
Antigen
Epitop
N-Term
9
3
3
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
22
3
2
2
2
2
1
1
Wirt
Kaninchen
14
5
3
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
20
5
3
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HAO2
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977848.
Sequenz DDNIAAFKRI RLRPRYLRDV SEVDTRTTIQ GEEISAPICI APTGFHCLVW
Homologie Cow: 85%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 93%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against HAO2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung HAO2
Hintergrund HAO2 is one of three related proteins that have 2-hydroxyacid oxidase activity yet differ in amino acid sequence, tissue expression and substrate preference. Subcellular location of the protein is the peroxisome. Specifically, the protein is expressed predominantly in liver and kidney and has the highest activity toward the substrate 2-hydroxypalmitate. Two alternatively spliced variants encoding the same isoform have been described.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed predominantly in liver and kidney and has the highest activity toward the substrate 2-hydroxypalmitate. Two alternatively spliced variants encoding the same isoform have been described.
Alias Symbols: GIG16, HAOX2
Protein Interaction Partner: PEX5,
Protein Size: 351
Molekulargewicht 39 kDa
Gen-ID 51179
NCBI Accession NM_001005783, NP_001005783
UniProt Q9NYQ3
Forschungsgebiet Cardiovascular, Fatty Acids, Metabolism, Organelles
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 351 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Hydroxyacid Oxidase 2 (HAO2) (N-Term) antibody (ABIN2773784) WB Suggested Anti-HAO2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Allgemeine Veröffentlichungen Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: "The DNA sequence and biological annotation of human chromosome 1. ..." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).

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