Septin 1 Antikörper

Produktnummer ABIN272245

Produktdetails anti-Septin 1 Antikörper

Target: Septin 1 (SEPT1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Septin 1 protein. (region surrounding Asp205)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Septin 1

Target: Septin 1 (SEPT1)

Andere Bezeichnung: Septin-1 (SEPT1) (SEPT1 Produkte)

Synonyme: DIFF6 antikoerper, LARP antikoerper, PNUTL3 antikoerper, SEP1 antikoerper, CG1403 antikoerper, Diff6 antikoerper, Dmel\\CG1403 antikoerper, anon-19Fa antikoerper, iby antikoerper, sep1 antikoerper, tu1 antikoerper, Pnutl3 antikoerper, SEPT1 antikoerper, Septin-1 antikoerper, septin 1 antikoerper, Septin 1 antikoerper, pfam02452; PemK antikoerper, SEPT1 antikoerper, Sep1 antikoerper, Sept1 antikoerper, sepT1 antikoerper

Hintergrund: The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGFβ signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGFβ or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.Synonyms: DIFF6, LARP, NY-BR-24, PNUTL3, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24

Molekulargewicht: approx. 40 kDa

Gen-ID: 1731

NCBI Accession: NP_443070

UniProt: Q8WYJ6