FOSL2 Antikörper
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- Target Alle FOSL2 Antikörper anzeigen
- FOSL2 (FOS-Like Antigen 2 (FOSL2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FOSL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of Fra-2/FOSL2 protein. (region surrounding Ser301)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Reinheit
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product FOSL2 Primärantikörper
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- Applikationshinweise
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FOSL2 (FOS-Like Antigen 2 (FOSL2))
- Andere Bezeichnung
- Fos-Related Antigen 2 (FOSL2 Produkte)
- Synonyme
- FOSL2 antikoerper, FRA2 antikoerper, Fra-2 antikoerper, Fra2 antikoerper, fra2 antikoerper, wu:fl17h04 antikoerper, xx:fl17h04 antikoerper, zgc:158347 antikoerper, PLB1 antikoerper, fra-2 antikoerper, FOS like 2, AP-1 transcription factor subunit antikoerper, fos-like antigen 2 antikoerper, FOSL2 antikoerper, Fosl2 antikoerper, fosl2 antikoerper
- Hintergrund
- The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70 % homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B, which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.Synonyms: FOSL2, FRA-2, FRA2
- Molekulargewicht
- approx. 42 kDa
- Gen-ID
- 2355
- NCBI Accession
- NP_005244
- UniProt
- P15408
- Pathways
- Feeding Behaviour, Photoperiodism
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