ARHGEF2 Antikörper (AA 2-447)

Produktnummer ABIN264980

Produktdetails anti-ARHGEF2 Antikörper

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Bindungsspezifität: AA 2-447

Reaktivität: Maus

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Spezifität: This antibody recognizes LCF.

Aufreinigung: Purified

Immunogen: Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 4 μg/mL, Detects a 118 kDa band in mouse tissue extracts corresponding towild-type Lfc. Immunoprecipitation: 4 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline and 0.08 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Andere Bezeichnung: ARHGEF2 (ARHGEF2 Produkte)

Synonyme: MGC82333 antikoerper, MGC86214 antikoerper, MGC75855 antikoerper, AA408978 antikoerper, GEF antikoerper, GEF-H1 antikoerper, GEFH1 antikoerper, LFP40 antikoerper, Lbcl1 antikoerper, Lfc antikoerper, P40 antikoerper, mKIAA0651 antikoerper, GEF-H1/LFC antikoerper, Rho/Rac guanine nucleotide exchange factor 2 antikoerper, Rho/Rac guanine nucleotide exchange factor 2 S homeolog antikoerper, rho/rac guanine nucleotide exchange factor (GEF) 2 antikoerper, ARHGEF2 antikoerper, arhgef2.S antikoerper, arhgef2 antikoerper, Arhgef2 antikoerper

Hintergrund: Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway.Synonyms: GEF-H1, Guanine nucleotide exchange factor H1, KIAA0651, LFP40, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, Rho guanine nucleotide exchange factor 2

Gen-ID: 16800

NCBI Accession: NP_001185840

UniProt: Q60875

Pathways: Negative Regulation of intrinsic apoptotic Signaling