Synthetic peptide corresponding to aa (Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys) of human BNP2.
Klon
9H6B4
Isotyp
IgG1
Applikationshinweise
IHC(P):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
-20 °C
Informationen zur Lagerung
BNP2 monoclonal antibody can be stored at -20 °C, stable for one year.
Target
BNP2
Hintergrund
BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.