RNF128 Antikörper
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- Target Alle RNF128 Antikörper anzeigen
- RNF128 (Ring Finger Protein 128 (RNF128))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF128 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF128.
- Top Product
- Discover our top product RNF128 Primärantikörper
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- Applikationshinweise
- RNF128 antibody can be used for detection of RNF128 by ELISA at 1:312500. RNF128 antibody can be used for detection of RNF128 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF128 antibody at -20 °C.
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- Target
- RNF128 (Ring Finger Protein 128 (RNF128))
- Andere Bezeichnung
- RNF128 (RNF128 Produkte)
- Synonyme
- rnf128 antikoerper, wu:fb57h05 antikoerper, zgc:77843 antikoerper, 1300002C13Rik antikoerper, AI987883 antikoerper, GRAIL antikoerper, Greul1 antikoerper, RGD1566282 antikoerper, grail antikoerper, greul1 antikoerper, ring finger protein 128a antikoerper, ring finger protein 128, E3 ubiquitin protein ligase antikoerper, ring finger protein 128 antikoerper, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antikoerper, rnf128a antikoerper, RNF128 antikoerper, Rnf128 antikoerper, rnf128.L antikoerper
- Hintergrund
- RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Molekulargewicht
- 47 kDa, 45 kDa
- Gen-ID
- 79589
- NCBI Accession
- NP_919445
- UniProt
- Q8TEB7
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