SSX2 Antikörper

Produktnummer ABIN2461583

Produktdetails anti-SSX2 Antikörper

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SSX2.

Anwendungsinformationen

Applikationshinweise: SSX2 antibody can be used for detection of SSX2 by ELISA at 1:62500. SSX2 antibody can be used for detection of SSX2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SSX2 antibody at -20 °C.

Details zu SSX2

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Andere Bezeichnung: SSX2 (SSX2 Produkte)

Synonyme: CT5.2 antikoerper, CT5.2A antikoerper, HD21 antikoerper, HOM-MEL-40 antikoerper, SSX antikoerper, SSX2 antikoerper, SSX3 antikoerper, SSX family member 2 antikoerper, protein SSX2 antikoerper, synovial sarcoma, X breakpoint 2 antikoerper, SSX2 antikoerper, LOC741661 antikoerper, Ssx2 antikoerper

Hintergrund: SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Molekulargewicht: 25 kDa

Gen-ID: 6757

NCBI Accession: NP_003138