YAF2 Antikörper
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- Target Alle YAF2 Antikörper anzeigen
- YAF2 (YY1 Associated Factor 2 (YAF2))
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Reaktivität
- Human, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser YAF2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YAF2.
- Top Product
- Discover our top product YAF2 Primärantikörper
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- Applikationshinweise
- YAF2 antibody can be used for detection of YAF2 by ELISA at 1:62500. YAF2 antibody can be used for detection of YAF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store YAF2 antibody at -20 °C.
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- Target
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Andere Bezeichnung
- YAF2 (YAF2 Produkte)
- Synonyme
- MGC75686 antikoerper, YAF2 antikoerper, zgc:136577 antikoerper, si:ch211-155a11.5 antikoerper, 2810021M11Rik antikoerper, YY1 associated factor 2 antikoerper, YY1-associated factor 2 antikoerper, yaf2 antikoerper, YAF2 antikoerper, LOC100221270 antikoerper, Yaf2 antikoerper
- Hintergrund
- YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.
- Molekulargewicht
- 20 kDa
- Gen-ID
- 10138
- NCBI Accession
- NP_005739
- UniProt
- Q8IY57
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