REC8 Antikörper

Produktnummer ABIN2459159

Produktdetails anti-REC8 Antikörper

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REC8.

Anwendungsinformationen

Applikationshinweise: REC8 antibody can be used for detection of REC8 by ELISA at 1:1562500. REC8 antibody can be used for detection of REC8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store REC8 antibody at -20 °C.

Details zu REC8

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Andere Bezeichnung: REC8 (REC8 Produkte)

Synonyme: Rec8L1 antikoerper, mrec antikoerper, HR21spB antikoerper, REC8L1 antikoerper, Rec8p antikoerper, REC8 meiotic recombination protein antikoerper, REC8 homolog (yeast) antikoerper, REC8 antikoerper, Rec8 antikoerper

Hintergrund: REC8 is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Molekulargewicht: 62 kDa

Gen-ID: 9985

NCBI Accession: NP_005123

UniProt: O95072