A1CF Antikörper

Produktnummer ABIN2458553

Produktdetails anti-A1CF Antikörper

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A1CF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A1CF.

Anwendungsinformationen

Applikationshinweise: A1CF antibody can be used for detection of A1CF by ELISA at 1:1562500. A1CF antibody can be used for detection of A1CF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store A1CF antibody at -20 °C.

Details zu A1CF

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Andere Bezeichnung: A1CF (A1CF Produkte)

Synonyme: ACF antikoerper, ACF64 antikoerper, ACF65 antikoerper, APOBEC1CF antikoerper, ASP antikoerper, 1810073H04Rik antikoerper, Acf antikoerper, A1cft antikoerper, Apobec-1 antikoerper, acf antikoerper, acf64 antikoerper, acf65 antikoerper, apobec1cf antikoerper, asp antikoerper, A1CF antikoerper, APOBEC1 complementation factor antikoerper, apobec1 complementation factor antikoerper, APOBEC1 complementation factor L homeolog antikoerper, A1CF antikoerper, A1cf antikoerper, a1cf antikoerper, a1cf.L antikoerper

Hintergrund: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.

Molekulargewicht: 65 kDa

Gen-ID: 29974

NCBI Accession: NP_620311

UniProt: Q9NQ94