POU1F1 Antikörper

Produktnummer ABIN2457941

Produktdetails anti-POU1F1 Antikörper

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU1F1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU1F1.

Anwendungsinformationen

Applikationshinweise: POU1F1 antibody can be used for detection of POU1F1 by ELISA at 1:312500. POU1F1 antibody can be used for detection of POU1F1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU1F1 antibody at -20 °C.

Details zu POU1F1

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Andere Bezeichnung: POU1F1 (POU1F1 Produkte)

Synonyme: CPHD1 antikoerper, GHF-1 antikoerper, PIT1 antikoerper, POU1F1a antikoerper, Pit-1 antikoerper, Hmp1 antikoerper, Pit1 antikoerper, Pit1-rs1 antikoerper, dw antikoerper, dwarf antikoerper, GHF1 antikoerper, GHF1A antikoerper, PIT1Z antikoerper, PIT-1 antikoerper, Pit-1* antikoerper, pit1 antikoerper, pit-1 antikoerper, POU class 1 homeobox 1 antikoerper, POU domain, class 1, transcription factor 1 antikoerper, POU1F1 antikoerper, Pou1f1 antikoerper, pou1f1 antikoerper

Hintergrund: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 33 kDa

Gen-ID: 5449

NCBI Accession: NP_000297

UniProt: P28069

Pathways: Regulation of Carbohydrate Metabolic Process