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Antikörper
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anti-CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper
CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper
| Antigen |
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| Synonyme |
FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3 |
| Klonalität |
Monoklonal (TR9) |
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Wirt
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Reaktivität
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Applikation
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Durchflusszytometrie (FACS) (170), Western Blot (WB) (77), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (63), Immunpräzipitation (IP) (41), Immunfluoreszenz (IF) (34), Immunhistochemie (Paraffinschnitte) (IHC (p)) (29), Immunhistochemie (IHC) (23), ELISA (16), Blocking Antibody (Inhibition) (7), Enzyme Immunoassay (EIA) (7), Funktionale Studien (Func) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunzytochemie (ICC) (4), Neutralisierung (Neut) (3), Blockierende Antikörper (Inhibition) (1), Dot Blot (Dot) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
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| Produktnummer |
ABIN238510 |
| Menge |
0.1 mg (1.0 mg/ml) |
| Preis |
180,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4, Plateletglycoprotein 4, Platelet glycoprotein IV, Platelet collagen receptor, Fatty acid translocase
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Weitere Bezeichnung
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CD36
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Swiss-Prot
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P16671
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Immunogen
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Platelets.
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Kreuzreaktivität
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Human
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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TR9
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Beschreibung
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CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs tothe class B family of scavenger receptors. CD36 is expressed by most resting marginal zoneB cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells invitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, butmodulates both primary and secondary antibody response. Similarly to glucose transporterGLUT4, CD36 is translocated from intracellular pools to the plasma membrane followingcell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception oflong-chain fatty acids.
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Spezifität
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The antibody TR9 reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoproteinexpressed on platelets, macrophages, endothelial cells, early erythroid cells andmegakaryocytes. This antibody cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e. g. adherence of infected erythrocytes totarget cells). Species: Human. Others not tested.
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Applikationshinweise
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Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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1.0 mg/ml
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Reinigung
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Purified
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Buffer
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20 mM Tris/HCl, pH~7.4 with 15 mM Sodium Azide as preservative
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
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Forschungsgebiet
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Krebs, Artherosklerose, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "CD36 Molecule (thrombospondin Receptor) (CD36)", Typ "Antikörper" finden
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Wirte
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Maus (172), Kaninchen (33), Hamster (15), Ratte (15), Ziege (1)
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Reaktivitäten
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Human (170), Maus (63), Ratte (Rattus) (24), Rind (Kuh) (4), Hamster (4), Kaninchen (4), Schwein (3), Hund (2), Affe (2)
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Applikationen
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Durchflusszytometrie (FACS) (170), Western Blot (WB) (77), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (63), Immunpräzipitation (IP) (41), Immunfluoreszenz (IF) (34), Immunhistochemie (Paraffinschnitte) (IHC (p)) (29), Immunhistochemie (IHC) (23), ELISA (16), Blocking Antibody (Inhibition) (7), Enzyme Immunoassay (EIA) (7), Funktionale Studien (Func) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunzytochemie (ICC) (4), Neutralisierung (Neut) (3), Blockierende Antikörper (Inhibition) (1), Dot Blot (Dot) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
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Konjugate
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FITC (33), PE (16), Biotin (12), APC (7), HRP (4), APC,Cy7 (2), Alexa Fluor 488 (2), Alexa Fluor 647 (2), Pacific Blue (2), RPE (2)
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Epitope
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extracellular domain (6), transcript variant 3 (3), Center (1)
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Alternativen 
