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CD14 Molecule (CD14) Antikörper (Biotin)

Antigen	CD14 Molecule (CD14)
Synonyme	CD14
Klonalität	Monoklonal (MEM-18)
Wirt	Alternativen Maus Maus (365), Kaninchen (41), Ratte (35), Ziege (9), Huhn (3)
Reaktivität	Alternativen Human Human (388), Maus (63), Hund (54), Affe (40), Schwein (37), Rind (Kuh) (32), Schaf (28), Cynomolgus (25), Rhesusaffen (25), Kaninchen (24), Primaten (19), Ratte (Rattus) (19), Primate (14), Katze (9), Ziege (9), Pferd (2), Pavian (1), Huhn (1), Schimpanse (1), Llama (1)
Konjugat	Alternativen Biotin FITC (55), PE (46), Biotin (38), APC (27), PerCP,Cy5.5 (10), Pacific Blue (8), RPE (8), Alexa Fluor 488 (6), PE,Cy7 (6), APC,Cy7 (5), Alexa Fluor 647 (5), Cy5.5 (5), Alexa Fluor 700 (4), Cy5 (2), Cy7,PE (2), EFluor 450 (2), EFluor 605NC (2), PE,Cy5 (2), PE,DY590 (2), PE,DY647 (2), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), CF (1), Cy3 (1), Cy7 (1), DY590 (1), DY647 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), PerCP (1), RBITC (1), RPE,Cy5 (1), RPE,Cy5.5 (1)
Applikation	Alternativen Durchflusszytometrie (FACS) Durchflusszytometrie (FACS) (369), Western Blot (WB) (71), Immunpräzipitation (IP) (58), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (46), ELISA (37), Immunfluoreszenz (IF) (35), Enzyme Immunoassay (EIA) (32), Funktionale Studien (Func) (32), Immunhistochemie (IHC) (29), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Blockierende Antikörper (Inhibition) (5), ELISA (Detektionsantikörper) (5), Immunzytochemie (ICC) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Radioimmunoassay (RIA) (2), Immunoelectron Microscopy (IEM) (1)

Produktnummer	ABIN238455
Menge	0.1 mg (1.0 mg/ml)
Preis	230,00 € Zzgl. Versandkosten €20,00 und MWSt
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Verfügbarkeit	Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
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Weitere Bezeichnung	CD14
Swiss-Prot	P08571
Immunogen	A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
Kreuzreaktivität	Human, Affe
Isotyp	IgG1
Klon	MEM-18
Beschreibung	CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes. Alternate Names: LPS-receptor.
Spezifität	The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes, also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.

Anwendungen
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Applikationshinweise	Suitable for indirect Immunofluorescence analysis by Flow Cytometry: Suggested working dilution is 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration	1.0 mg/ml
Buffer	PBS, pH 7.4 with 15 mM sodium azide as preservative.
Lagerung	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf Life: One year from despatch.
Forschungsgebiet	Stammzellen, Angeborene Immunität, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Immunologie, Inflammation
Beschränkungen	Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen zurück nach oben

Alternativen zu Antigen "CD14 Molecule (CD14)", Typ "Antikörper" finden

Wirte	Maus (365), Kaninchen (41), Ratte (35), Ziege (9), Huhn (3)
Reaktivitäten	Human (388), Maus (63), Hund (54), Affe (40), Schwein (37), Rind (Kuh) (32), Schaf (28), Cynomolgus (25), Rhesusaffen (25), Kaninchen (24), Primaten (19), Ratte (Rattus) (19), Primate (14), Katze (9), Ziege (9), Pferd (2), Pavian (1), Huhn (1), Schimpanse (1), Llama (1)
Applikationen	Durchflusszytometrie (FACS) (369), Western Blot (WB) (71), Immunpräzipitation (IP) (58), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (46), ELISA (37), Immunfluoreszenz (IF) (35), Enzyme Immunoassay (EIA) (32), Funktionale Studien (Func) (32), Immunhistochemie (IHC) (29), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Blockierende Antikörper (Inhibition) (5), ELISA (Detektionsantikörper) (5), Immunzytochemie (ICC) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Radioimmunoassay (RIA) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate	FITC (55), PE (46), Biotin (38), APC (27), PerCP,Cy5.5 (10), Pacific Blue (8), RPE (8), Alexa Fluor 488 (6), PE,Cy7 (6), APC,Cy7 (5), Alexa Fluor 647 (5), Cy5.5 (5), Alexa Fluor 700 (4), Cy5 (2), Cy7,PE (2), EFluor 450 (2), EFluor 605NC (2), PE,Cy5 (2), PE,DY590 (2), PE,DY647 (2), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), CF (1), Cy3 (1), Cy7 (1), DY590 (1), DY647 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), PerCP (1), RBITC (1), RPE,Cy5 (1), RPE,Cy5.5 (1)
Epitope	C-Term (2), N-Term (2)