AIF Antikörper (AA 593-606)

Produktnummer ABIN211058

Der Kaninchen Polyklonal anti-AIF Antikörper wird verwendet zum Nachweis von AIF in Proben von Human, Ratte, Maus, Schwein, Rind (Kuh), Hund, Pferd, Kaninchen, Affe, Hamster und Fledermaus. Er wurde validiert für WB.

Kurzübersicht für AIF Antikörper (AA 593-606) (ABIN211058)

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Hund, Pferd, Kaninchen, Affe, Hamster, Fledermaus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AIF Antikörper

Bindungsspezifität: AA 593-606

Spezifität: Recognizes AIF, Mr 57kD. Another non-specific protein was also detected at Mr 120kD. Species cross-reactivity: Mouse. Predicted for human and rat based on sequence homology.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Cat, Horse, Rabbit, Pig (100%) Opossum, Xenopus (92%) Turkey, Chicken, Stickleback, Pufferfish, Zebrafish (83%).

Aufreinigung: Protein A purified

Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 593-606 of human Apoptosis Inducing Factor, AIF (C-KDGEQHEDLNEV-AK), containing a N-terminal cysteine. The immunizing sequence is identical in mouse and rat. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Cat, Horse, Rabbit, Pig (100%), Opossum, Xenopus (92%), Turkey, Chicken, Stickleback, Pufferfish, Zebrafish (83%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: WB (1 μg/mL)

Usage: Suitable for use in Western Blot. Western Blot Analysis: 1 μg/mL detects AIF from a mouse liver preparation. Mouse liver protein preparation was resolved by electrophoresis, transferred to nitrocellulose and probed with AIF (1 μg/mL). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 200 μg of protein A purified rabbit IgG in 200 μLof 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol. Liquid at -20 deg C.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu AIF

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Andere Bezeichnung: AIFM1 / AIF / PDCD8

Hintergrund: Name/Gene ID: AIFM1
Family: Apoptosis

Synonyms: AIFM1, AIF, COXPD6, PDCD8, Programmed cell death 8

Gen-ID: 9131

UniProt: O95831

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effekt