MDM2 Antikörper (pSer185)
Kurzübersicht für MDM2 Antikörper (pSer185) (ABIN201305)
Target
Alle MDM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 177-198, pSer185
-
Spezifität
- Recognizes mouse MDM 2 showing a band at ~102kD corresponding to phosphorylated MDM2. Cellular Localization: Nuclear and cytoplasmic. Expressed predominantly in the nucleoplasm. Interaction with ARF (P14) results in the localization of both proteins to the nucleus. The nucleolar localization signals in both ARF and MDM2 may be necessary to allow efficient nucleolar localization of both proteins.
-
Aufreinigung
- Immunoaffinity purified
-
Immunogen
-
A synthetic peptide corresponding to aa177-198, hrkrrrslsfdpslglcel of mouse MDM2.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Approved: ELISA (1:1000 - 1:5000), WB (1:1000)
Usage: Suitable for use in ELISA and Western Blot. ELISA: 1:1000-1:5000. Western Blot: 1:1000. -
Kommentare
-
Target Species of Antibody: Mouse
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- PBS, pH 7.2, 0.1 % sodium azide. No stabilizing proteins added.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
-
-
- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
-
Andere Bezeichnung
- MDM2
-
Hintergrund
-
Name/Gene ID: MDM2
Synonyms: MDM2, ACTFS, Double minute 2 protein, Hdm2, MDM2 variant FB30, HDMX, Oncoprotein Mdm2, p53-binding protein Mdm2, MDM2 variant FB28 -
Gen-ID
- 4193
-
UniProt
- Q00987
-
Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Autophagie, Ubiquitin Proteasome Pathway
Target
-