PAPSS1 Antikörper (N-Term)

Produktnummer ABIN1882107

Produktdetails anti-PAPSS1 Antikörper

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPSS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PAPSS1.

Klon: RB5122

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PAPSS1 Antikörper (ABIN1882107)

Gillies, Lee, Long, Ktistakis, Pyne, Pyne: "The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division." in: Cellular signalling, Vol. 21, Issue 5, pp. 675-84, (2009) (PubMed).

Venkatachalam: "Human 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase: biochemistry, molecular biology and genetic deficiency." in: IUBMB life, Vol. 55, Issue 1, pp. 1-11, (2003) (PubMed).

Xu, Otterness, Freimuth, Carlini, Wood, Mitchell, Moon, Kim, Xu, Siciliano, Weinshilboum: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 437-44, (2000) (PubMed).

Venkatachalam, Akita, Strott: "Molecular cloning, expression, and characterization of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase and its functional domains." in: The Journal of biological chemistry, Vol. 273, Issue 30, pp. 19311-20, (1998) (PubMed).

Faiyaz ul Haque, King, Krakow, Cantor, Rusiniak, Swank, Superti-Furga, Haque, Abbas, Ahmad, Ahmad, Cohn: "Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse." in: Nature genetics, Vol. 20, Issue 2, pp. 157-62, (1998) (PubMed).

Girard, Baekkevold, Amalric: "Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 12, Issue 7, pp. 603-12, (1998) (PubMed).

Details zu PAPSS1

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Andere Bezeichnung: PAPSS1 (PAPSS1 Produkte)

Synonyme: ATPSK1 antikoerper, PAPSS antikoerper, SK1 antikoerper, AI325286 antikoerper, Asapk antikoerper, papss1 antikoerper, MGC82588 antikoerper, atpsk1 antikoerper, papss antikoerper, sk1 antikoerper, PAPSS1 antikoerper, wu:fc43e12 antikoerper, zgc:194984 antikoerper, zgc:194985 antikoerper, CG8363 antikoerper, DmPAPSS antikoerper, Dmel\\CG8363 antikoerper, PAPS antikoerper, Paps antikoerper, l(3)76BDn antikoerper, paps antikoerper, 3'-phosphoadenosine 5'-phosphosulfate synthase 1 antikoerper, bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 antikoerper, bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 antikoerper, PAPS synthetase antikoerper, PAPSS1 antikoerper, Papss1 antikoerper, papss1 antikoerper, papss1.L antikoerper, LOC100543301 antikoerper, LOC100637112 antikoerper, Papss antikoerper

Hintergrund: Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

Molekulargewicht: 70833

NCBI Accession: NP_005434

UniProt: O43252

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process