NEK6 Antikörper (N-Term)
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- Target Alle NEK6 Antikörper anzeigen
- NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
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Bindungsspezifität
- AA 8-39, N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NEK6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This NEK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-39 amino acids from the N-terminal region of human NEK6.
- Klon
- RB2965
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NEK6 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis." in: British journal of cancer, Vol. 99, Issue 8, pp. 1307-15, (2008) (PubMed).
: "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases." in: The Journal of biological chemistry, Vol. 278, Issue 37, pp. 34897-909, (2003) (PubMed).
: "Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and ..." in: The Journal of biological chemistry, Vol. 277, Issue 31, pp. 27839-49, (2002) (PubMed).
: "Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase." in: Biochemical and biophysical research communications, Vol. 293, Issue 2, pp. 753-8, (2002) (PubMed).
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Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis." in: British journal of cancer, Vol. 99, Issue 8, pp. 1307-15, (2008) (PubMed).
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- Target
- NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
- Andere Bezeichnung
- NEK6 (NEK6 Produkte)
- Synonyme
- 1300007C09Rik antikoerper, si:ch211-167p9.4 antikoerper, ATNEK5 antikoerper, MOE17.17 antikoerper, NIMA-RELATED KINASE5 antikoerper, NIMA-related kinase 5 antikoerper, SID6-1512 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 6 antikoerper, NIMA-related kinase 6 antikoerper, NIMA related kinase 6 antikoerper, Serine/Threonine kinase catalytic domain protein antikoerper, NIMA-related kinase 6 S homeolog antikoerper, Nek6 antikoerper, nek6 antikoerper, NEK6 antikoerper, NEK5 antikoerper, nek6.S antikoerper
- Hintergrund
- NEK6 is a serine/threonine kinase that controls initiation of mitosis. NEK6 is activated during M phase. It is required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis.
- Molekulargewicht
- 35714
- NCBI Accession
- NP_001138473, NP_001159639, NP_001159640, NP_001159641, NP_001159642, NP_001159643, NP_055212
- UniProt
- Q9HC98
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