GTF2E1 Antikörper (C-Term)
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- Target Alle GTF2E1 Antikörper anzeigen
- GTF2E1 (General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GTF2E1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- VADDPIVMVA GRPFSYSEVS QRPELVAQMT PEEKEAYIAM GQRMFEDLFE
- Kreuzreaktivität
- Rind (Kuh), Hund, Fruchtfliege (Drosophila melanogaster), Human, Maus, Ratte (Rattus)
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GTF2E1. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2E1
- Top Product
- Discover our top product GTF2E1 Primärantikörper
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- Applikationshinweise
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WB Suggested Anti-GTF2 E1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Daudi cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Kommentare
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Antigen size: 439 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GTF2E1 (General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1))
- Andere Bezeichnung
- GTF2E1 / TF2E1 (GTF2E1 Produkte)
- Synonyme
- 2610024P03Rik antikoerper, 56kDa antikoerper, AI303800 antikoerper, FE antikoerper, TFIIE-A antikoerper, DDBDRAFT_0168201 antikoerper, DDBDRAFT_0168202 antikoerper, DDBDRAFT_0231096 antikoerper, DDB_0168201 antikoerper, DDB_0168202 antikoerper, DDB_0231096 antikoerper, DDBDRAFT_0217176 antikoerper, DDBDRAFT_0217177 antikoerper, DDBDRAFT_0266401 antikoerper, DDB_0217176 antikoerper, DDB_0217177 antikoerper, DDB_0266401 antikoerper, TF2E1 antikoerper, si:ch211-194d6.2 antikoerper, gtf2e1 antikoerper, tfiiealpha antikoerper, general transcription factor II E, polypeptide 1 (alpha subunit) antikoerper, general transcription factor IIE subunit 1 antikoerper, transcription factor IIE antikoerper, general transcription factor IIE subunit 2 antikoerper, general transcription factor IIE, polypeptide 2, beta 34kDa antikoerper, general transcription factor IIE, polypeptide 1, alpha antikoerper, general transcription factor IIE subunit 1 L homeolog antikoerper, Gtf2e1 antikoerper, gtf2e1-1 antikoerper, gtf2e1-2 antikoerper, GTF2E2 antikoerper, GTF2E1 antikoerper, gtf2e1 antikoerper, gtf2e1.L antikoerper
- Hintergrund
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The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57,000 (TFIIE-alpha) and 34,000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation
Alias Symbols: FE, TF2E1, TFIIE-A
Protein Interaction Partner: UBC, AARSD1, ACBD3, XPO5, SH3GLB2, OXR1, NSUN2, RPUSD2, SNF8, EFTUD2, TTC1, SH3GL1, SARS, HARS, SRPK2, TCEA1, GTF2H1, GTF2E2, CDK7, APP, tat, GTF2F1, ELAVL1, ZSCAN1, ZBTB9, TRIM15, PCBD2, TRIM29, CBFA2T2, IKBKG, ATF7IP, TAF6, GTF2B, TRIM24, SND1, GTF2H4,
Protein Size: 439 - Molekulargewicht
- 49 kDa
- Gen-ID
- 2960
- NCBI Accession
- NM_005513, NP_005504
- UniProt
- P29083
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