RRN3 Antikörper (Middle Region)

Produktnummer ABIN183013

Produktdetails anti-RRN3 Antikörper

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VDGKVDNGKT KDLYRDLINI FDKLLLPTHA SCHVQFFMFY LCSFKLGFAE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 650 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Andere Bezeichnung: RRN3 (RRN3 Produkte)

Synonyme: RRN3 antikoerper, DKFZp459B073 antikoerper, CG16938 antikoerper, CG3278 antikoerper, CG5951 antikoerper, Dmel\\CG3278 antikoerper, TIF-1A antikoerper, TIF-IA antikoerper, Tif-1A antikoerper, TifIA antikoerper, dTIF-IA antikoerper, dyak_GLEANR_13182 antikoerper, DyakGE12956 antikoerper, GE12956 antikoerper, Tif-IA antikoerper, A-270G1.2 antikoerper, TIFIA antikoerper, RGD1305001 antikoerper, AL023001 antikoerper, E130302O19Rik antikoerper, R75565 antikoerper, Tif1a antikoerper, RRN3 homolog, RNA polymerase I transcription factor antikoerper, RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) antikoerper, CG3278 gene product from transcript CG3278-RA antikoerper, GE12956 gene product from transcript GE12956-RA antikoerper, RRN3 homolog, RNA polymerase I transcription factor L homeolog antikoerper, RRN3 RNA polymerase I transcription factor homolog (yeast) antikoerper, RRN3 antikoerper, rrn3 antikoerper, Tif-IA antikoerper, Dyak\Tif-IA antikoerper, rrn3.L antikoerper, Rrn3 antikoerper

Hintergrund: In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.
Alias Symbols: TIFIA, A-270G1.2
Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
Protein Size: 650

Molekulargewicht: 74 kDa

Gen-ID: 54700

NCBI Accession: NM_018427, NP_060897

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling