PSMD14 Antikörper (N-Term)

Produktnummer ABIN182576

Der Kaninchen Polyklonal anti-PSMD14 Antikörper wird verwendet zum Nachweis von PSMD14 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Kaninchen, Pferd und Hund. Er wurde validiert für WB und IHC.

Kurzübersicht für PSMD14 Antikörper (N-Term) (ABIN182576)

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PSMD14 Antikörper

Bindungsspezifität: N-Term

Sequenz: MDRLLRLGGG MPGLGQGPPT DAPAVDTAEQ VYISSLALLK MLKHGRAGVP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMD14. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 310 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Andere Bezeichnung: PSMD14

Hintergrund: POH1 (pad one homolog-1) is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway (Spataro et al., 1997 [PubMed 9374539]).
Alias Symbols: PAD1, POH1, RPN11
Protein Interaction Partner: FAM9B, DPY30, HUWE1, UBC, PSMD7, MEOX2, UBE3C, SHFM1, UBE3A, RAD23B, PSME2, PSME1, PSMD13, PSMD12, PSMD11, PSMD10, PSMD8, PSME4, ADRM1, PSME3, PSMD6, PSMD4, PSMD3, PSMD2, PSMD1, PSMC6, PSMC5, PSMC4, PSMC3, PSMC2, PSMC1, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3,
Protein Size: 310

Molekulargewicht: 35 kDa

Gen-ID: 10213

NCBI Accession: NM_005805, NP_005796

UniProt: O00487

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway