Ggt5 Heavy Chain (Heavy Chain) Antikörper (PE)

Produktnummer ABIN1712728

Produktdetails

Target: Ggt5 Heavy Chain

Bindungsspezifität: Heavy Chain

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: PE

Applikation: Western Blotting (WB)

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 heavy chain

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Ggt5 Heavy Chain

Synonyme: GGT-REL antikoerper, GGTLA1 antikoerper, gamma-glutamyltransferase 5 antikoerper, GGT5 antikoerper

Hintergrund:

Synonyms: Gamma glutamyl transpeptidase related enzyme, Gamma glutamyltranspeptidase 5, Gamma-glutamyl transpeptidase-related enzyme, Gamma-glutamyltransferase 5 heavy chain, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, GGT 5, GGT REL, GGT-rel, GGT5, GGT5_HUMAN, DKFZP566O011, GGTLA1, Glutathione hydrolase 5, Leukotriene-C4 hydrolase, Gamma-glutamyltransferase 5 heavy chain.

Background: g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4, it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.

Gen-ID: 2687

UniProt: P36269