ZFP36L1 Antikörper (AA 101-200) (HRP)

Produktnummer ABIN1712413

Produktdetails anti-ZFP36L1 Antikörper (HRP)

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Bindungsspezifität: AA 101-200

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFP36L1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZFP36L1/ERF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Andere Bezeichnung: ZFP36L1/ERF1 (ZFP36L1 Produkte)

Synonyme: ZFP36L1 antikoerper, berg36 antikoerper, brf1 antikoerper, c3h-2 antikoerper, cmg1 antikoerper, erf-1 antikoerper, erf1 antikoerper, rnf162b antikoerper, tis11b antikoerper, BRF1 antikoerper, Berg36 antikoerper, ERF-1 antikoerper, ERF1 antikoerper, RNF162B antikoerper, TIS11B antikoerper, cMG1 antikoerper, Brf1 antikoerper, TIS11b antikoerper, AW742437 antikoerper, AW743212 antikoerper, D530020L18Rik antikoerper, cb198 antikoerper, cb480 antikoerper, fk89d11 antikoerper, id:ibd1247 antikoerper, sb:cb198 antikoerper, sb:cb480 antikoerper, wu:fb80h11 antikoerper, wu:fb92f07 antikoerper, wu:fk89d11 antikoerper, zfp36l1 antikoerper, zfp36l2 antikoerper, zgc:153979 antikoerper, fc06f10 antikoerper, wu:fc06f10 antikoerper, zfp36l1l antikoerper, zgc:77882 antikoerper, ZFP36 ring finger protein-like 1 S homeolog antikoerper, ZFP36 ring finger protein like 1 antikoerper, zinc finger protein 36, C3H type-like 1 antikoerper, zinc finger protein 36, C3H type-like 1a antikoerper, BRF1, RNA polymerase III transcription initiation factor subunit antikoerper, transcription factor IIIB 90 kDa subunit antikoerper, zinc finger protein 36, C3H type-like 1b antikoerper, zfp36l1.S antikoerper, ZFP36L1 antikoerper, Zfp36l1 antikoerper, zfp36l1a antikoerper, BRF1 antikoerper, LOC100350146 antikoerper, zfp36l1b antikoerper

Hintergrund:

Synonyms: Berg36, BRF1, Butyrate response factor 1, C3H1 type-like 1, cMG1, Early response factor Berg36, EGF response factor 1, EGF-response factor 1, ERF 1, ERF-1, ERF1, Protein TIS11B, RNF162B, TIS11B, TISB_HUMAN, ZFP36L1, Zinc finger protein 36, Zinc finger protein 36 C3H type like 1, zinc finger protein C3H type 36 like 1.

Background: TIS11B is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3?-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.

Gen-ID: 677