ASL Antikörper (AA 301-400) (HRP)
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- Target Alle ASL Antikörper anzeigen
- ASL (Argininosuccinate Lyase (ASL))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ASL Antikörper ist konjugiert mit HRP
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ASL/Argininosuccinate Lyase
- Isotyp
- IgG
- Top Product
- Discover our top product ASL Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ASL (Argininosuccinate Lyase (ASL))
- Andere Bezeichnung
- ASL/Argininosuccinate Lyase (ASL Produkte)
- Synonyme
- ASAL antikoerper, 2510006M18Rik antikoerper, zgc:63532 antikoerper, BA4879 antikoerper, PSPTO0125 antikoerper, Adl antikoerper, Asl antikoerper, argininosuccinate lyase antikoerper, argininosuccinate lyase ArgH antikoerper, adenylosuccinate lyase antikoerper, argininosuccinate lyase L homeolog antikoerper, ASL antikoerper, Asl antikoerper, asl antikoerper, argH2 antikoerper, argH antikoerper, arg7 antikoerper, CNC04420 antikoerper, STHERM_c13370 antikoerper, Adsl antikoerper, asl.L antikoerper, ARG7 antikoerper
- Hintergrund
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Synonyms: Argininosuccinase, Argininosuccinate lyase, Arginosuccinase, ARLY_HUMAN, ASAL, ASL, EC 4.3.2.1.
Background: ASL is a member of the lyase 1 family of proteins and is predominantly expressed in the liver. Localizing to the cytoplasm and existing as a homotetramer, ASL catalyzes the hydrolytic cleavage of argininosuccinic acid (ASA) to fumarate and arginine, an essential step of the urea cycle which is crucial for the detoxification of ammonia. This reaction is also involved in the biosynthesis of arginine. In addition, ASL shares high sequence homology with the avian and reptilian eye lens protein, d-crystallin. Mutations in the gene encoding ASL leads to an accumulation of ASA in body fluids and results in Arginosuc-cinic aciduria (ASAuria), an autosomal recessive disorder that is characterized by hyperammonemia, liver enlargement, convulsions, physical and mental retardation, episodic unconsciousness and dry and brittle hair showing trich-orrhexis nodosa (weak points or nodes in the hair shaft).
- Gen-ID
- 435
- Pathways
- Response to Growth Hormone Stimulus
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