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Antikörper
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anti-Activating Transcription Factor 2 ATF2 pThr69-51 pThr71-53
Activating Transcription Factor 2 (ATF2) (pThr69/51 + pThr71/53) Antikörper
| Antigen |
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| Synonyme |
HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420 |
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Epitope
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pThr69/51 (7), pSer62/44 (6), pThr71/53 (6), Ab-112 or 94 (5), Ab-62 or 44 (5), Ab-69 or 51 (5), Ab-71 or 53 (5), Ab-73 or 55 (5), pSer112 or 94 (5), pSer62 or 44 (5), pThr69 or 51 (5), pThr71 or 53 (5), pThr73 or 55 (5), pSer112/94 (4), pThr73/55 (4), S44 (2), S94 (2), pThr71 (2), PSer340/322 (1), S322 (1), pSer44 (1), pSer472 (1), pSer490 + pSer498 (1), pSer94 (1), pThr51 (1), pThr79/51 (1)
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Western Blot (WB) (118), Immunhistochemie (IHC) (63), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunfluoreszenz (IF) (39), Immunpräzipitation (IP) (38), Enzyme Immunoassay (EIA) (31), ELISA (24), Durchflusszytometrie (FACS) (14), Dot Blot (Dot) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunelektronenmikroskopie (EM) (1)
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| Produktnummer |
ABIN155094 |
| Menge |
0.1 mg (0.5 mg/ml) |
| Preis |
380,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Versandbereit innerhalb von 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: ATF-2, CREB2, CREBP1, Activating transcription factor 2, CRE-BP1, HB16, CREB-2, CyclicAMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2,cAMP response element-binding protein CRE-BP1, Cyclic AMP-responsive element-bindingprotein 2
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Weitere Bezeichnung
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ATF2 pThr69/51 + pThr71/53
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Swiss-Prot
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P15336
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Beschreibung
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The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family ofleucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiateCRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 bystress-activated kinases is necessary for transcriptional activation. Myc also inducesphosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 alsofunctions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B andH4 in vitro.
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Spezifität
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The antibody detects phosphorylated ATF-2 (Thr69 and Thr71). Species: Human, Mouse, Rat. Others not tested.
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Applikationshinweise
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Western Blot: 1-2 μg/ml. Immunoprecipitation: 10 μg/ml. Immunohistochemistry: 20 μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.5 mg/ml
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Buffer
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PBS, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide
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Lagerung
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Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Forschungsgebiet
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Zellzyklus, Signaltransduktion, Kinasen/Phosphatasen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Activating Transcription Factor 2 (ATF2)", Typ "Antikörper" finden
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Wirte
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Kaninchen (164), Maus (17), Ziege (5), Schaf (5)
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Reaktivitäten
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Human (186), Maus (127), Ratte (Rattus) (112), Huhn (2), Xenopus laevis (2), Rind (Kuh) (1), Hund (1), Pferd (1)
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Applikationen
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Western Blot (WB) (118), Immunhistochemie (IHC) (63), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunfluoreszenz (IF) (39), Immunpräzipitation (IP) (38), Enzyme Immunoassay (EIA) (31), ELISA (24), Durchflusszytometrie (FACS) (14), Dot Blot (Dot) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunelektronenmikroskopie (EM) (1)
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Konjugate
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Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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pThr69/51 (7), pSer62/44 (6), pThr71/53 (6), Ab-112 or 94 (5), Ab-62 or 44 (5), Ab-69 or 51 (5), Ab-71 or 53 (5), Ab-73 or 55 (5), pSer112 or 94 (5), pSer62 or 44 (5), pThr69 or 51 (5), pThr71 or 53 (5), pThr73 or 55 (5), pSer112/94 (4), pThr73/55 (4), S44 (2), S94 (2), pThr71 (2), PSer340/322 (1), S322 (1), pSer44 (1), pSer472 (1), pSer490 + pSer498 (1), pSer94 (1), pThr51 (1), pThr79/51 (1)
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