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Activating Transcription Factor 2 (ATF2) (pThr69/51 + pThr71/53) Antikörper

Antigen

Activating Transcription Factor 2 (ATF2)

Synonyme HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420
Epitope
Alternativen

pThr69/51 + pThr71/53

Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human, Maus, Ratte (Rattus)

Applikation
Alternativen Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN155094
Menge 0.1 mg  (0.5 mg/ml)
Preis 380,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Versandbereit innerhalb von 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: ATF-2, CREB2, CREBP1, Activating transcription factor 2, CRE-BP1, HB16, CREB-2, CyclicAMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2,cAMP response element-binding protein CRE-BP1, Cyclic AMP-responsive element-bindingprotein 2
Weitere Bezeichnung ATF2 pThr69/51 + pThr71/53
Swiss-Prot P15336
Beschreibung The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family ofleucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiateCRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 bystress-activated kinases is necessary for transcriptional activation. Myc also inducesphosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 alsofunctions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B andH4 in vitro.
Spezifität The antibody detects phosphorylated ATF-2 (Thr69 and Thr71). Species: Human, Mouse, Rat. Others not tested.

Anwendungen

Applikationshinweise Western Blot: 1-2 μg/ml. Immunoprecipitation: 10 μg/ml. Immunohistochemistry: 20 μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 0.5 mg/ml
Buffer PBS, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide
Lagerung Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Forschungsgebiet Zellzyklus, Signaltransduktion, Kinasen/Phosphatasen
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Activating Transcription Factor 2 (ATF2)", Typ "Antikörper" finden
Wirte Kaninchen (164), Maus (17), Ziege (5), Schaf (5)
Reaktivitäten Human (186), Maus (127), Ratte (Rattus) (112), Huhn (2), Xenopus laevis (2), Rind (Kuh) (1), Hund (1), Pferd (1)
Applikationen Western Blot (WB) (118), Immunhistochemie (IHC) (63), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunfluoreszenz (IF) (39), Immunpräzipitation (IP) (38), Enzyme Immunoassay (EIA) (31), ELISA (24), Durchflusszytometrie (FACS) (14), Dot Blot (Dot) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunelektronenmikroskopie (EM) (1)
Konjugate Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pThr69/51 (7), pSer62/44 (6), pThr71/53 (6), Ab-112 or 94 (5), Ab-62 or 44 (5), Ab-69 or 51 (5), Ab-71 or 53 (5), Ab-73 or 55 (5), pSer112 or 94 (5), pSer62 or 44 (5), pThr69 or 51 (5), pThr71 or 53 (5), pThr73 or 55 (5), pSer112/94 (4), pThr73/55 (4), S44 (2), S94 (2), pThr71 (2), PSer340/322 (1), S322 (1), pSer44 (1), pSer472 (1), pSer490 + pSer498 (1), pSer94 (1), pThr51 (1), pThr79/51 (1)