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Activating Transcription Factor 2 (ATF2) (pThr69/51 + pThr71/53) Antikörper
| Antigen | Activating Transcription Factor 2 (ATF2) |
| Synonyme | HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420 |
| Epitope |
Alternativen pThr69/51 + pThr71/53 |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Maus, Ratte (Rattus) |
| Applikation |
Alternativen Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
|
| Produktnummer | ABIN155094 |
| Menge | 0.1 mg (0.5 mg/ml) |
| Preis | 390,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Produktmerkmale | Synonyms: ATF-2, CREB2, CREBP1, Activating transcription factor 2, CRE-BP1, HB16, CREB-2, CyclicAMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2,cAMP response element-binding protein CRE-BP1, Cyclic AMP-responsive element-bindingprotein 2 |
| Weitere Bezeichnung | ATF2 pThr69/51 + pThr71/53 |
| Swiss-Prot | P15336 |
| Beschreibung | The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family ofleucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiateCRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 bystress-activated kinases is necessary for transcriptional activation. Myc also inducesphosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 alsofunctions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B andH4 in vitro. |
| Spezifität | The antibody detects phosphorylated ATF-2 (Thr69 and Thr71). Species: Human, Mouse, Rat. Others not tested. |
Anwendungen
| Applikationshinweise | Western Blot: 1-2 μg/ml. Immunoprecipitation: 10 μg/ml. Immunohistochemistry: 20 μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Konzentration | 0.5 mg/ml |
| Buffer | PBS, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide |
| Lagerung | Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Forschungsgebiet | Zellzyklus, Signaltransduktion, Kinasen/Phosphatasen |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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