XCL1 Antikörper (AA 21-114) (Cy3)

Produktnummer ABIN1408263

Produktdetails anti-XCL1 Antikörper (Cy3)

Target: XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))

Bindungsspezifität: AA 21-114

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XCL1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Lymphotactin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu XCL1

Target: XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))

Andere Bezeichnung: Lymphotactin/Xcl1 (XCL1 Produkte)

Synonyme: ATAC antikoerper, LPTN antikoerper, LTN antikoerper, SCM-1 antikoerper, SCM-1a antikoerper, SCM1 antikoerper, SCM1A antikoerper, SCYC1 antikoerper, AI661682 antikoerper, Lptn antikoerper, Scyc1 antikoerper, Ltn antikoerper, XCL1 antikoerper, XCL2 antikoerper, X-C motif chemokine ligand 1 antikoerper, chemokine (C motif) ligand 1 antikoerper, cytokine SCM-1 beta antikoerper, lymphotactin antikoerper, XCL1 antikoerper, Xcl1 antikoerper, LOC490356 antikoerper, LOC100714756 antikoerper, LOC100349255 antikoerper

Hintergrund:

Synonyms: Lptn, LTN, XCL1 C mot chemokine 1, SCM 1 alpha, ATAC, Chemokine C Mot Ligand 1, Cytokine SCM-1, LPTN, LTN, Lymphotactin, Lymphotaxin, SCM-1-alpha, SCM1, SCYC1, Small inducible cytokine C1, Small Inducible Cytokine Subfamily C Member 1, Small-inducible cytokine C1, XC chemokine ligand 1, Xcl1, XCL1_HUMAN.

Background: Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1). Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4). In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2). Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1). The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5). The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2).

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation