TCRgd Antikörper

Produktnummer ABIN135302

Produktdetails

Target: TCRgd

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse TCR

Produktmerkmale: Hamster Anti-Mouse TCRgd-UNLB

Aufreinigung: Purified

Immunogen: Mouse T cell clone G8

Klon: UC7-13D5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Depletion - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vivo depletion of gd TCR-expressing T cell

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Antigendetails

Target: TCRgd

Hintergrund: The TCR heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are + and have limited receptor diversity. The TCR heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.