RT1-BB Antikörper (PE)

Produktnummer ABIN133240

Produktdetails anti-RT1-BB Antikörper (PE)

Target: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Reaktivität: Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RT1-BB Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Aufreinigung: Purified from ascitic fluid via Protein G Chromatography.

Immunogen: rat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-AG4 (NS1/1) Specificity Rat RT1.B (Rat Ia-non-polymorphic) . Donor: BALB/c spleen

Klon: OX-6

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/ml

Buffer: R-PE conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu RT1-BB

Target: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Andere Bezeichnung: RT1.B (RT1-BB Produkte)

Synonyme: RT1.B antikoerper, RT1 class II, locus Bb antikoerper, RT1-Bb antikoerper

Hintergrund: Anti-rat RT1.B monoclonal antibody recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells (2,3,4) but not peripheral T lymphocytes. (4) This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC (1,2) and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized by ABIN133240is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography (1).

Pathways: Production of Molecular Mediator of Immune Response