CD63 Antikörper
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- Target Alle CD63 Antikörper anzeigen
- CD63
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD63 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Spezifität
- The antibody reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- HPB-ALL T cell line
- Klon
- MEM-259
- Isotyp
- IgG1
- Top Product
- Discover our top product CD63 Primärantikörper
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- Applikationshinweise
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Flow cytometry (detection of activated platelets, neutrophils and basophils). Immunoprecipitation. Western blotting under non-reducing conditions. Immunocytochemistry. Immunohistochemistry (paraffin sections): Recommended dilution:10 m g/mL, Positive tissue: spleen
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. General. - Haltbarkeit
- 12 months
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Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells." in: Cell communication and signaling : CCS, Vol. 9, Issue 1, pp. 4, (2011) (PubMed).
: "
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Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells." in: Cell communication and signaling : CCS, Vol. 9, Issue 1, pp. 4, (2011) (PubMed).
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- Target
- CD63
- Andere Bezeichnung
- CD63 (CD63 Produkte)
- Synonyme
- C75951 antikoerper, ME491 antikoerper, Tspan30 antikoerper, LAMP-3 antikoerper, MLA1 antikoerper, OMA81H antikoerper, TSPAN30 antikoerper, TSP29FA antikoerper, CD63 antigen antikoerper, CD63 molecule antikoerper, Cd63 molecule antikoerper, Cd63 antikoerper, CD63 antikoerper
- Hintergrund
- CD63, a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.Synonyms: Granulophysin, ME491, MLA1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, TSPAN30, Tetraspanin-30
- Gen-ID
- 967
- UniProt
- P08962
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