Chemokine (C-C Motif) Ligand 8 (CCL8) Antikörper

Details zu Produkt Nr. ABIN116143, Anbieter: Anmelden zum Anzeigen
Antigen
  • HC14
  • MCP-2
  • MCP2
  • SCYA10
  • SCYA8
  • 1810063B20Rik
  • AB023418
  • Mcp2
  • Scya8
  • chemokine (C-C motif) ligand 8
  • monocyte chemoattractant protein-2 precursor
  • CCL8
  • Ccl8
  • MCP-2
Reaktivität
Human
92
51
3
2
1
Wirt
Kaninchen
73
39
15
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
15
7
6
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
102
58
15
14
8
6
4
4
4
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Highly pure (>98%) recombinant hMCP-2.
Spezifität Human Macrophage Chemotactic Protein-2 (MCP-2).
Reinigung Affinity chromatography.
Andere Bezeichnung MCP2 / CCL8 (CCL8 Antibody Abstract)
Hintergrund MCP 2 (Monocyte Chemoattractant Protein 2) is a chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. MCP 2 is important to inflammatory host responses, and is found in the highest concentration in the small intestine and peripheral blood cells. This protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.Synonyms: C-C motif chemokine 8, CCL-8, HC14, MCP-2, Monocyte Chemotactic Protein-2, Monocyte chemoattractant protein 2, SCYA10, SCYA8, Small-inducible cytokine A8
Gen-ID 6355
NCBI Accession NP_005614
UniProt P80075
Forschungsgebiet Cytokines, Chemokines
Applikationshinweise Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhMCP-2 (100.00 ng/mL), a concentration of 12-16 μg/mL of this antibody is required. ELISA: To detect hMCP-2 by Indirect ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5-0.2 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hMCP-2. Sandwich: To detect hMCP-2 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with Biotinylated Anti-Human MCP-2 (PP1045B1/B2) as adetection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinanthMCP-2. Western Blot: To detect hMCP-2 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hMCP-2 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
Buffer PBS, pH 7.2 without preservatives.
Konservierungsmittel Without preservative
Handhabung Centrifuge vial prior to opening!
Lagerung 4 °C
Informationen zur Lagerung Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
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