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Antikörper
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anti-Interleukin 6 (IL6) Antikörper (Biotin)
Interleukin 6 (IL6) Antikörper (Biotin)
| Antigen |
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| Synonyme |
HGF, HSF, BSF2, IL-6, IFNB2, Il-6, ILg6, Ifnb2, IL6, il-6 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Konjugat
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Applikation
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Enzyme Immunoassay (EIA) (59), Western Blot (WB) (58), ELISA (24), Funktionale Studien (Func) (17), Immunpräzipitation (IP) (13), Durchflusszytometrie (FACS) (11), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Neutralisierung (Neut) (10), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Immunfluoreszenz (IF) (8), ELISPOT (6), Blockierende Antikörper (Inhibition) (2), Dot Blot (Dot) (2), Immunhistochemie (IHC) (2), Elektromobilitäts-Experimente (EMSA) (1), Immunzytochemie (ICC) (1), Immunoradiometrisches Assay (IRMA) (1), Intrazellulärfärbung (IS) (1), Radioimmunoassay (RIA) (1)
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| Produktnummer |
ABIN115883 |
| Menge |
25 µg (Varianten) |
| Preis |
230,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF, Hybridoma growthfactor, CTL differentiation factor
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Weitere Bezeichnung
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Interleukin-6 (IL6)
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Gen-ID
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16193
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Swiss-Prot
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P08505
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Immunogen
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Highly pure (>98%) recombinant mIL-6
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Beschreibung
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Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the mediumof RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNFalpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to bedirectly involved in the responses that occur after infection and cellular injury, and it mayprove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6has also been implicated in regulating adipose mass. IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes ormacrophages and endothelial cells. It acts upon a variety of cells including fibroblasts,myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears tointeract with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferativeeffect of IL3 on multipotential hematopoietic progenitors.
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Spezifität
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Detects murine IL-6. Species: Mouse. Others not tested. Add. Information: Centrifuge vial prior to opening!
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Applikationshinweise
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ELISA: (Direct): To detect mIL-6 by direct ELISA (using 100 μl/well antibody solution) aconcentration of 0.25-1.0 μg/ml of this antibody is required. This biotinylated polyclonalantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant mIL-6. (Sandwich): To detect mIL-6 by sandwich ELISA (using 100 μl/well antibody solution) aconcentration of 0.25 - 1.0 μg/ml of this antibody is required. This biotinylated polyclonalantibody, in conjunction with Polyclonal Anti-Murine IL-6 (PP012P) as a capture antibody,allows the detection of at least 0.2-0.4 ng/well of recombinant mIL-6.
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Buffer
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PBS, pH 7.2 without preservatives.Label: BiotinReconstitution: Restore in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0mg/ml.
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Lagerung
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Store the antibody prior to reconstitution at -20°C. Following reconstitution the antibodycan be stored at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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Forschungsgebiet
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Zytokine, Rezeptoren, Inflammation, Immunologie, Virologie, Krebs
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Interleukin 6 (IL6)", Typ "Antikörper" finden
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Wirte
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Kaninchen (33), Maus (32), Ratte (27), Ziege (9), Huhn (1), Schaf (1)
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Reaktivitäten
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Human (57), Maus (25), Ratte (Rattus) (12), Schaf (4), Rind (Kuh) (3), Huhn (2), Affe (2), Pavian (1)
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Applikationen
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Enzyme Immunoassay (EIA) (59), Western Blot (WB) (58), ELISA (24), Funktionale Studien (Func) (17), Immunpräzipitation (IP) (13), Durchflusszytometrie (FACS) (11), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Neutralisierung (Neut) (10), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Immunfluoreszenz (IF) (8), ELISPOT (6), Blockierende Antikörper (Inhibition) (2), Dot Blot (Dot) (2), Immunhistochemie (IHC) (2), Elektromobilitäts-Experimente (EMSA) (1), Immunzytochemie (ICC) (1), Immunoradiometrisches Assay (IRMA) (1), Intrazellulärfärbung (IS) (1), Radioimmunoassay (RIA) (1)
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Konjugate
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Biotin (17), FITC (3), PE (1)
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Alternativen 
