Chemokine (C-C Motif) Ligand 8 (CCL8) Antikörper

Details zu Produkt Nr. ABIN115779, Anbieter: Anmelden zum Anzeigen
Antigen
  • HC14
  • MCP-2
  • MCP2
  • SCYA10
  • SCYA8
  • 1810063B20Rik
  • AB023418
  • Mcp2
  • Scya8
  • chemokine (C-C motif) ligand 8
  • monocyte chemoattractant protein-2 precursor
  • CCL8
  • Ccl8
  • MCP-2
Reaktivität
Human
92
51
3
2
1
Wirt
Maus
74
38
15
1
Klonalität
Monoklonal
Konjugat
Unkonjugiert
15
7
6
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
102
58
15
14
8
6
4
4
4
2
2
1
1
Optionen
Hersteller
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Immunogen Highly pure (>98%) recombinant Human MCP-2
Isotyp IgG1
Spezifität Reacts with Human Macrophage Chemotactic Protein-2 (MCP-2)
Reinigung Affinity Chromatography on Protein A
Andere Bezeichnung MCP2 / CCL8 (CCL8 Antibody Abstract)
Hintergrund MCP 2 (Monocyte Chemoattractant Protein 2) is a chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. MCP 2 is important to inflammatory host responses, and is found in the highest concentration in the small intestine and peripheral blood cells. This protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.Synonyms: C-C motif chemokine 8, CCL-8, HC14, MCP-2, Monocyte Chemotactic Protein-2, Monocyte chemoattractant protein 2, SCYA10, SCYA8, Small-inducible cytokine A8
Gen-ID 6355
NCBI Accession NP_005614
UniProt P80075
Forschungsgebiet Cytokines, Chemokines
Applikationshinweise ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 1.0-2.0 μg/mL of thisantibody will detect at least 100 pg/mL of recombinant human MCP-2 when used withBiotin anti-Human MCP-2 antibody (cat. PP1047B) as the detection antibody at aconcentration of approximately 0.5-1.0 μg/mL. Western Blot: To detect Human MCP-2 by Western Blot analysis this antibody can be usedat a concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMCP-2 is 0.25-0.50 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofHuman MCP-2 (100 ng/mL), a concentration of 0.8-1.0 μg/mL of this antibody is required.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Restore in sterile water to a concentration of 1.0 mg/mL.
Buffer PBS without preservatives
Konservierungsmittel Without preservative
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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